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Metformin Tablet: A Comprehensive Guide to Uses, Side Effects, and Dosage

Metformin Tablet: A Comprehensive Guide to Uses, Side Effects, and Dosage – Metformin is a widely prescribed medication used to manage type 2 diabetes mellitus. It belongs to the class of drugs known as biguanides and is often sold under the brand name Glucophage. In this comprehensive guide, we will explore the uses, side effects, dosage, and important considerations regarding Metformin tablets.

Metformin Tablet: A Comprehensive Guide to Uses, Side Effects, and Dosage

Uses of Metformin Tablet

  1. Diabetes Management: Metformin is primarily used to lower blood sugar levels in individuals with type 2 diabetes. It works by improving the body’s response to insulin, a hormone that regulates blood sugar.
  2. Polycystic Ovary Syndrome (PCOS): Metformin is also prescribed for women with PCOS who have insulin resistance, as it can help regulate menstrual cycles and improve fertility.

How Metformin Works

Metformin’s primary mechanism of action involves:

  • Reducing the amount of sugar produced by the liver.
  • Increasing the sensitivity of muscle cells to insulin, allowing them to absorb more sugar from the bloodstream.
  • Slowing down the absorption of sugar from the digestive tract.

Dosage and Administration

The dosage of Metformin varies depending on individual needs and medical conditions. Typically, the starting dose for adults with type 2 diabetes is 500 mg to 850 mg taken orally once a day with meals. The dose may be gradually increased to achieve optimal blood sugar control.

It’s crucial to follow your healthcare provider’s instructions regarding dosage and timing. Taking Metformin with food can help reduce gastrointestinal side effects such as nausea and diarrhea.

Side Effects

While Metformin is generally well-tolerated, some individuals may experience side effects. Common side effects include:

  1. Gastrointestinal Issues: Nausea, diarrhea, and stomach discomfort are common but usually temporary side effects. Starting with a lower dose and gradually increasing it can help minimize these symptoms.
  2. Vitamin B12 Deficiency: Long-term use of Metformin may lead to a deficiency in vitamin B12. Regular monitoring and supplementation may be necessary.
  3. Lactic Acidosis (Rare): Although extremely rare, lactic acidosis is a severe side effect that can be life-threatening. Seek immediate medical attention if you experience symptoms such as muscle pain, weakness, or difficulty breathing.
  4. Hypoglycemia: While Metformin alone doesn’t typically cause low blood sugar (hypoglycemia), it can increase the risk if combined with other diabetes medications or insulin.

It’s important to inform your healthcare provider about any side effects or concerns you may have while taking Metformin.

Precautions and Considerations

  • Inform your healthcare provider about any medical conditions, allergies, or medications you are currently taking before starting Metformin.
  • Alcohol consumption should be limited while taking Metformin, as it can increase the risk of lactic acidosis.
  • Regular blood sugar monitoring and follow-up appointments with your healthcare provider are essential to ensure the medication is effectively managing your condition.
  • Metformin is not recommended for individuals with severe kidney or liver disease.


Metformin tablets are a valuable tool in managing type 2 diabetes and, in some cases, polycystic ovary syndrome. When used as prescribed and monitored by a healthcare provider, Metformin can help stabilize blood sugar levels and improve overall health. However, it’s crucial to be aware of potential side effects, follow dosage instructions, and communicate openly with your healthcare team throughout your treatment journey. Always consult with your healthcare provider for personalized advice on the use of Metformin and its suitability for your specific medical needs.

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